Chlorpheniramine facilitates inhibitory avoidance in teleosts submitted to telencephalic ablation
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منابع مشابه
Chlorpheniramine facilitates inhibitory avoidance in teleosts submitted to telencephalic ablation.
The present study investigated the involvement of H(1) histaminegic receptor on the acquisition of inhibitory avoidance in Carassius auratus submitted to telencephalic ablation. The fish were submitted to telencephalic ablation 5 days before the experiment. The inhibitory avoidance procedure included 1 day for habituation, 3 days for training composed of 3 trials each (1st day: T1, T2, T3; 2nd ...
متن کاملChlorpheniramine impairs functional recovery in Carassius auratus after telencephalic ablation.
We determined the effect of an H1 receptor antagonist on the functional recovery of Carassius auratus submitted to telencephalic ablation. Five days after surgery the fish underwent a spatial-choice learning paradigm test. The fish, weighing 6-12 g, were divided into four groups: telencephalic ablation (A) or sham lesion (S) and saline (SAL) or chlorpheniramine (CPA, ip, 16 mg/kg). For eight co...
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The effect of post-training treatment with L-histidine (LH) on the memory consolidation of inhibitory avoidance was investigated in Carassius auratus submitted to cerebellar ablation. The inhibitory avoidance procedure included 3 days: one habituation day, one training day (5 trials, T1-T5) and one test day. On the training day, each fish was placed individually in a white compartment separated...
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The zebrafish (Danio rerio) is increasingly being used as model in behavioural [1,2], neurobiological and genetic research [3]. Underlying reasons are high genetic homology to humans [4] and the many advantages over the use of rodents, such as low cost, easy handling, short reproduction cycle and high fecundity. Furthermore, its genome [5], transcriptome [6] and proteome [7] are well described,...
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The present study was aimed at developing a new inhibitory avoidance task, based on training and/or testing rats in multiple contexts, to investigate accuracy of memory. In the first experiment, male Sprague-Dawley rats were given footshock in an inhibitory avoidance apparatus and, 48 h later, retention latencies of each rat were assessed in the training apparatus (Shock box) as well as in a no...
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ژورنال
عنوان ژورنال: Brazilian Journal of Medical and Biological Research
سال: 2008
ISSN: 1414-431X,0100-879X
DOI: 10.1590/s0100-879x2008005000015